A semi and a half-ton collided on Highway 4 about eight kilometres north of North Battleford Friday morning, sending one person to hospital via STARS with serious injuries.
Police were called to the scene at just before 8 a.m. and the airlift operation, cleanup and investigation kept the highway closed for several hours.
Traffic was rerouted until just after 1 p.m.
North Battleford Fire Department were called upon to use their extrication equipment to free occupants.
North Battleford RCMP say the investigation is ongoing and police will be updating, sometime this afternoon, the condition of the male driver of one of the vehicles, who was airlifted to hospital.